ONE2FILL™
Single-Use, Simultaneous Filling
One2Fill™ 10x simultaneous aliquoting solution streamlines up- and downstream bioprocessing applications, including media or buffer preparations, sampling, and drug substance filling with speed, precision, and simplicity.
10X FASTER ALIQUOTING
40 SECOND
SETUP
20X LOWER
CAPEX
SIMPLIFYING UP AND DOWNSTREAM BIOPROCESSING APPLICATIONS
10X FASTER FILLING
Our innovative One Vent Hub enables the simultaneous, aseptic and precise distribution of liquid via a single feeding line into up to 10 containers.
+/- 3% ACCURACY FOR PRECISION FILLING
High-accuracy simultaneous bottle-filling in volumes ranging from 125 mL to 2 L, reduces hold-up volume and lowers your drug manufacturing footprint.
ONLY 1 VENT FILTER TO TEST
We significantly reduce the effort and time required for vent filter integrity testing, minimizing this effort by a factor of 10 with our One Vent Hub solution.
SIGNIFICANT SETUP TIME SAVINGS
One2Fill™ installs in just 40 seconds. Aseptically connect to the feed line, start filling, disconnect the bottles, and you’re ready.
RELIABLE AND SECURE
Using our PharmaTainer™ bottles ensures super clean processing. Our drop test-proven PharmaTainer is exceptionally strong and oustandigly clean: <1.7 % of the USP 788 limits with 0 detectable endotoxins. Our one-piece molded cap solution, Cap2V8®, combined with our One Vent Hub solution ensures that the most critical connections don’t use cable-ties.
APPLICATIONS
One2Fill™ is used in the most demanding modalities and workflows in bioprocessing, advanced therapies and custom applications.
THE FIRST SIMULTANEOUS BOTTLE FILLING SYSTEM
Reduces vent integrity testing time requirements and provides a filling accuracy of ± 3%.
Offers robust connections free from cable-ties.
Our one-piece molded tube and cap solution reduces the risk of contamination and product loss associated with barbed fittings.
Outstandingly clean and strong containers ensure super clean, reliable processing. Available in 125 mL, 250 mL, 500 mL, 1 L and 2 L.
Offers easy handling and installation with just one connection.
ONE2FILL™ COMPONENTS
ADDITIONAL SINGLE-USE SOLUTIONS
Single-use, out-of-the-box bottle and carboy small-volume mixing platform.
Simultaneous bottle filling system for bioprocessing.
Automated roller bottle processing system for adherent cell culture stages.
One2Fill™ Aliquoting System FAQ
What is One2Fill™?
One2Fill is SaniSure’s simultaneous aliquoting system that fills up to 10 containers at once through a single aseptic feed line. The One2Fill One Vent Hub carries the vent path for every container in the set, supporting media and buffer filling, sampling, and drug substance filling.
How accurate is One2Fill’s simultaneous bottle filling?
One2Fill fills within ±3% accuracy across container volumes from 125 mL to 2 L. Because One2Fill fills every container in parallel from one feed line, it also reduces hold-up volume and manufacturing footprint compared with filling bottles one at a time.
How long does One2Fill take to set up?
One2Fill installs in about 40 seconds. An operator connects the assembly aseptically to the feed line, fills all containers simultaneously, then disconnects the bottles. A fill that runs serially on single-bottle systems becomes one short operation on One2Fill, whatever the container count.
Why does One2Fill only require testing one vent filter?
The One2Fill One Vent Hub routes all 10 containers through a single shared vent filter, so only one filter requires integrity testing. That reduces vent filter integrity testing effort by a factor of 10 compared with systems that fit an individual vent filter to every container.
What containers and applications does One2Fill support?
One2Fill uses PharmaTainer™ bottles from 125 mL to 2 L with Cap2V8® caps and CellGyn® tubing. One2Fill supports media and buffer filling, sampling, drug substance filling, and feed aliquoting, and can be configured with custom containers including bags and conical vessels.
GET MORE INFORMATION
We’d love to discuss how SaniSure® can streamline your operations, reduce risks, and drive growth in your drug filling capabilities.