
RC-40™
Automated Roller Bottle Processing
The Roller Cell 40™ (RC-40) is a roller bottle cell culture system that fully automates all adherent cell culture stages-from inoculation, incubation, and media change to trypsinization and final harvest.
Unlike manual tissue culture bottles, the RC-40™ delivers a completely closed system for aseptic operation, and a single operator can process the equivalent of up to 200 standard roller bottles.

1 OPERATOR AUTOMATION

100% ASEPTIC SYSTEM
SETUP

40 ROLLER BOTTLES AT ONCE

MAXIMUM CONSISTENCY,
RELIABILITY AND EFFICIENCY
REDUCE RISK WITH CLOSED SYSTEM CELL CULTURE
The RC-40™ delivers a fully closed system cell culture workflow, eliminating the contamination risks associated with manual roller bottle processing. The result is a more aseptic flow path with less process variation and more reliable, repeatable results.
UNLOCK EFFICIENCY WITH A FULLY AUTOMATED SOLUTION
A single operator can quickly and homogeneously fill 40 5X roller bottles, the equivalent of 200 standard bottles, for roller bottle cell culture, perform media exchange in 10–15 minutes, and harvest in just 5–10 minutes-all without opening a single bottle. Standardized, reproducible roller bottle culture processes offer automated batch records aligned with FDA, EMA, and ICH frameworks.
REDUCE LABOR COSTS
The RC-40™ has the potential to reduce your labor costs by up to 95% with its parallel versus sequential flow path, single operator automation, and the reduction of operator interventions.
INCREASE YIELD AND STABILITY
With expanded surface bottles, you can experience higher yields while retaining your existing production process.
REDUCE LAB OCCUPANCY FOOTPRINT
This compact system can significantly reduces lab space occupancy allowing you to increase your production without having to invest in facility expansion.
APPLICATIONS
The RC-40™ is used in the most demanding modalities and workflows in bioprocessing and advanced therapies.
Recombinant Proteins
Viral Vaccines
Vectors Vero Cell Expansion
REDUCING RISK AND TIME AND LABOR COSTS
A gamma-irradiated RC-40™ bottle pack includes 20 single-use roller bottles serving as a closed, ready-to-use alternative to standard tissue culture bottles or roller bottle apparatus pre-assembled with tubing, manifolds, and filters, accessible via a single aseptic connection.
Each fitted with a consistent multichannel peristaltic pump that enables homogeneous filling.
Pump volume, rotor direction (both clock and counterclockwise), and speed are controlled with a multi-color touchscreen that features password protection, alarm histories, remote operation and multi-language capabilities.
Provides strength and security for the structure of the RC-40™.
ADDITIONAL SINGLE-USE SOLUTIONS

Single-use, out-of-the-box bottle and carboy small-volume mixing platform.

Bespoke final fill assemblies designed entirely around your drug product.

Simultaneous bottle filling system for bioprocessing.
GET MORE INFORMATION
We’d love to discuss how SaniSure® can streamline your operations, reduce risks, and drive growth in your drug filling capabilities.